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Talaga, D. S.; Jia, Y.; Bopp, M. A.; Sytnik, A.; DeGrado, W. A.; Cogdell, R. J.; Hochstrasser, R. M.  “Single-molecule dynamics associated with protein folding and deformations of light-harvesting complexes” Springer Series in Chemical Physics (Single Molecule Spectroscopy: Nobel Conference Lectures), (2002), 67, 313-325.

We are developing new approaches to single molecule measurements to enhance our ability to extract useful information from them. Innovations include data acquisition and instrument automation, incorporation of microfluidics, development of new labeling methods, and investigation of various immobilization schemes.